BRUE Risk Stratification

Name: BRUE Risk Stratification
Creator: Daniel Diaz-Gil, MD
Keywords: BRUE, Brief Resolved Unexplained Event, ALTE, apparent life-threatening event, apnea, infant, risk stratification, AAP 2016

AAP 2016 risk classification for Brief Resolved Unexplained Events in infants

Clinically Verified· 5 tests

For educational and informational purposes only. Verify all results before clinical application.

Age at Event *

Event Duration *

CPR Required by Trained Medical Provider? *

CPR performed by a trained medical provider, not bystander CPR

History of Prematurity (<32 weeks) or Corrected Age <45 weeks? *

Born at <32 weeks gestational age OR corrected gestational age <45 weeks at event

First Event? *

Identifiable Cause Found? *

e.g., GER, seizure, respiratory infection, choking episode

References

Tieder JS, Bonkowsky JL, Etzel RA, et al. Brief Resolved Unexplained Events (Formerly Apparent Life-Threatening Events) and Evaluation of Lower-Risk Infants. Pediatrics. 2016;137(5):e20160590.[DOI]

Reviewed by Daniel Diaz-Gil, MD · Last updated March 2026

Medical disclaimer

This tool is for educational and informational purposes only. It is not a substitute for professional clinical judgment. Always independently verify results before making clinical decisions.

Professional Resources — Tools used by pediatricians for general pediatric care

The Harriet Lane HandbookClassic pediatric drug dosing and clinical reference~$50via Amazon Broselow Pediatric Emergency TapeColor-coded length-based tape for weight estimation and emergency dosing~$30via Amazon